Hemorrhoidal Cream, Maximum Strength (with Pramoxine HCl 1%)
Preparation H and its twins. Protectant / Vasoconstrictor / Local anesthetic. Active ingredients: Glycerin 14.4% + Phenylephrine HCl 0.25% + Pramoxine HCl 1% + White petrolatum 15%.
14 options at Walmart, Target, Kroger, Walgreens, CVS, Amazon. Cheapest: $4.92 per oz; typical Preparation H: $11.14 per oz. Prices are estimates from Oct 2026.
Cheapest options
- Equate Hemorrhoidal Cream Maximum Strength Pain Relief — Walmart, 51 g, $8.97 ($4.92 per oz)
- up&up Hemorrhoid Cream Maximum Strength Pain Relief — Target, 51 g, $9.49 ($5.21 per oz)
- Kroger Hemorrhoidal Cream Maximum Strength Pain Relief — Kroger, 51 g, $9.99 ($5.48 per oz)
- Walgreens Hemorrhoidal Cream Maximum Strength Pain Relief — Walgreens, 51 g, $12.49 ($6.86 per oz)
- CVS Health Hemorrhoidal Cream Maximum Strength Pain Relief — CVS, 51 g, $12.99 ($7.13 per oz)
- Preparation H Maximum Strength Pain Relief Hemorrhoidal Cream — Walmart, 51 g, $15.47 ($8.49 per oz)
- Walgreens Hemorrhoidal Cream Maximum Strength Pain Relief — Walgreens, 25.5 g, $7.99 ($8.77 per oz)
- Preparation H Maximum Strength Pain Relief Hemorrhoidal Cream — Amazon, 51 g, $15.99 ($8.78 per oz)
Where to find it
Look for the “Digestive Health” aisle sign.
Good to know
- Preparation H's cream and ointment are different formulas: the Maximum Strength cream adds pramoxine HCl 1% (a local anesthetic) and glycerin and is for external use only, while the ointment is mineral oil and petrolatum and may also be used inside the rectum.
- Preparation H Rapid Relief cream uses lidocaine 5% instead of pramoxine — a different formula, not in this group.