Guaifenesin 600 mg Extended-Release (12 HR)
Mucinex and its twins. Expectorant. Active ingredients: Guaifenesin 600 mg.
17 options at Walmart, Amazon, Target, Kroger, CVS, Walgreens. Cheapest: 25¢ per pill; typical Mucinex: 65¢ per pill. Prices are estimates from Oct 2026.
Cheapest options
- Equate Mucus Relief ER 600 mg Tablets — Walmart, 40 tablets, $9.97 (25¢ per pill)
- Amazon Basic Care Mucus ER 600 mg Tablets — Amazon, 40 tablets, $9.99 (25¢ per pill)
- up&up Mucus Relief ER 600 mg Tablets — Target, 40 tablets, $11.99 (30¢ per pill)
- Kroger Mucus Relief ER 600 mg Tablets — Kroger, 40 tablets, $11.99 (30¢ per pill)
- CVS Health Mucus Relief ER 600 mg Tablets — CVS, 40 tablets, $17.99 (45¢ per pill)
- Walgreens Mucus Relief ER 600 mg Tablets — Walgreens, 40 tablets, $17.99 (45¢ per pill)
- Mucinex 12 Hour Chest Congestion Expectorant — Walmart, 40 tablets, $19.97 (50¢ per pill)
- Mucinex 12 Hour Chest Congestion Expectorant — Amazon, 40 tablets, $21.49 (54¢ per pill)
Where to find it
Look for the “Cough, Cold & Flu” aisle sign.
Good to know
- Mucinex Maximum Strength contains 1,200 mg guaifenesin per tablet — twice the amount — so it is a separate group.
- The Mucinex name covers many different formulas: Mucinex DM adds dextromethorphan (a cough suppressant), Mucinex D adds pseudoephedrine (sold from behind the pharmacy counter), and Mucinex Fast-Max and Sinus-Max products add ingredients such as acetaminophen or phenylephrine.