Esomeprazole 20 mg
Nexium 24HR and its twins. Acid reducer. Active ingredients: Esomeprazole 20 mg.
18 options at Costco, Walmart, Amazon, Target, Kroger, CVS, Walgreens. Cheapest: 33¢ per capsule; typical Nexium 24HR: 94¢ per capsule. Prices are estimates from Oct 2026.
Cheapest options
- Kirkland Signature Esomeprazole Magnesium Delayed-Release Capsules 20 mg — Costco, 42 capsules, $13.99 (33¢ per capsule)
- Equate Esomeprazole Magnesium Delayed-Release Capsules 20 mg — Walmart, 42 capsules, $15.94 (38¢ per capsule)
- Amazon Basic Care Esomeprazole Magnesium Delayed-Release Capsules 20 mg — Amazon, 42 capsules, $15.99 (38¢ per capsule)
- up&up Esomeprazole Magnesium Delayed-Release Capsules 20 mg — Target, 42 capsules, $17.99 (43¢ per capsule)
- Kroger Esomeprazole Magnesium Delayed-Release Capsules 20 mg — Kroger, 42 capsules, $19.99 (48¢ per capsule)
- Nexium 24HR Esomeprazole Magnesium Delayed-Release Capsules 20 mg — Walmart, 42 capsules, $27.47 (65¢ per capsule)
- Nexium 24HR Esomeprazole Magnesium Delayed-Release Capsules 20 mg — Amazon, 42 capsules, $27.49 (65¢ per capsule)
- CVS Health Esomeprazole Magnesium Delayed-Release Capsules 20 mg — CVS, 42 capsules, $28.99 (69¢ per capsule)
Where to find it
Look for the “Digestive Health” aisle sign.
Good to know
- Nexium 24HR's Drug Facts list esomeprazole 20 mg per capsule, corresponding to 22.3 mg esomeprazole magnesium trihydrate; store brands list the same 20 mg dose.
- Nexium 24HR is sold as regular capsules, smaller "Clear Minis" capsules and tablets — all esomeprazole 20 mg.
- A 42-capsule box is three 14-day courses — compare by capsule, not by box.