Aspirin 81 mg (Low Dose)
Bayer and its twins. Pain reliever. Active ingredients: Aspirin 81 mg. Also sold as St. Joseph Low Dose, Ecotrin Low Strength.
27 options at Walmart, Costco, Target, Kroger, CVS, Amazon, Walgreens. Cheapest: 1.3¢ per pill; typical Bayer: 9.2¢ per pill. Prices are estimates from Oct 2026.
Cheapest options
- Equate Low Dose Aspirin 81 mg Enteric Coated Tablets — Walmart, 300 tablets, $3.98 (1.3¢ per pill)
- Kirkland Signature Low Dose Aspirin 81 mg Enteric Coated Tablets (2 × 365) — Costco, 730 tablets, $9.99 (1.4¢ per pill)
- Equate Low Dose Aspirin 81 mg Enteric Coated Tablets — Walmart, 120 tablets, $1.97 (1.6¢ per pill)
- up&up Low Dose Aspirin 81 mg Coated Tablets — Target, 300 tablets, $4.99 (1.7¢ per pill)
- Kroger Low Dose Aspirin 81 mg Coated Tablets — Kroger, 120 tablets, $2.99 (2.5¢ per pill)
- Equate Chewable Low Dose Aspirin 81 mg — Walmart, 36 tablets, $1.24 (3.4¢ per pill)
- CVS Health Low Dose Aspirin 81 mg Enteric Coated Tablets — CVS, 300 tablets, $10.79 (3.6¢ per pill)
- Amazon Basic Care Chewable Low Dose Aspirin 81 mg — Amazon, 120 tablets, $4.49 (3.7¢ per pill)
Where to find it
Look for the “Pain Relief” aisle sign.
Good to know
- "Low dose", "low strength" and "regimen" aspirin labeled 81 mg are all the same dose; safety-coated (enteric) and chewable tablets are both 81 mg.
- Bayer Aspirin Regimen also comes as a 325 mg enteric-coated tablet — four times the dose — in similar packaging, so check for "81 mg".
- Chewable 81 mg tablets are not coated; the coated tablets' label says their delayed action will not give fast relief.